Innovation Pharmaceuticals Inc (IPIX)

[farrell90]

Brilacidin inhaler from 11/12/2021 PR

"Initial feasibility work to formulate Brilacidin for potential prophylactic use via inhaled delivery, to leverage Brilacidin’s unique virucidal and blocking antiviral properties, also is underway."

http://www.ipharminc.com/press-release/2021/11/12/innovation-pharmaceuticals-conducting-full-data-analysis-of-phase-2-brilacidin-covid-19-trial-results-to-support-brilacidins-potential-inclusion-in-government-sponsored-covid-19-trials

Contrary to recent criticism of your post, protein based inhaled drugs are currently approved therapeutics { eg insulin and many others} and more are being studied. See table 1. from the link below.

https://link.springer.com/article/10.1186/s43556-020-00014-z

239 peptide or protein based drugs are reported to be approved in this 2017 data base.

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0181748

The article is a good review of the promises and technical issues in formulating inhaled drugs.

Inhaled drugs are now commonly used. Many people with asthma and COPD use inhaled pharmaceuticals. Ask someone with severe asthma where their inhalers are and they frequently will pull them out of their pockets or purses.

http://www.ipharminc.com/press-release/2021/11/12/innovation-pharmaceuticals-conducting-full-data-analysis-of-phase-2-brilacidin-covid-19-trial-results-to-support-brilacidins-potential-inclusion-in-government-sponsored-covid-19-trials

Brilacidin will not be the first drug for covid where an inhaler was studied. Gilead has completed a clinical trial for remdesivir to be used as an inhaler.

https://clinicaltrials.gov/ct2/show/NCT04539262

Many inhaled drugs, including peptides and proteins, have been approved and many more are being studied. Given Brilacidin's potent antiviral in vitro studies as well as its safety it is more than reasonable to study Brilacidin as an inhaled therapeutic.

GLTA Farrell