I've heard it said they use an algorithm that attempts to handle intraday shorts, to mitigate the risk they faced with short squeezes on stocks like Gamestop. The computers ladder short sells and market sells to drive down price, then they cover intraday for a small profit, leaving things reset at end of day so they can continue tomorrow or avert if there's news. I'll have to dig around to find the links but the strategy makes sense to me.
With this approach they've allegedly been able to short the whole OTC without onloading any risk. If it's true, it's blatant market manipulation, but the SEC looks the other way.
Companies can push back by releasing real news on the regular, and not pre-announcing it. ENZC releases news rarely and sometimes teases it ahead of time, so it bleeds. But it has a lot of things going for it that other OTCs lack, and a very supportive investor base - surely it'll have its day!