Where the results look excellent, the safety profile is excellent but legacy oncology players will be throwing stones from the shadows about different aspects of this trial, and we all know that will be the case whether it is through AF or elsewhere, it won’t matter, the peer review will provide political cover that the FDA is not far out there, and given recent decisions, that can’t be undersold as a benefit for this particular trial, which has consistently looked fantastic and been made to look like a failure, by all the known and usual players.