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Steady_T

08/31/21 10:47 AM

#328393 RE: Bourbon_on_my_cornflakes #328390

Here is ACIU news. Note: It slowed the rate of decline and met one of two primary end points. Bolding is mine.

AC Immune SA on Tuesday said a Phase 2 study evaluating the safety and efficacy of its investigational anti-tau monoclonal antibody semorinemab in mild-to-moderate Alzheimer's disease met one of its co-primary endpoints.

The Lausanne, Switzerland, clinical-stage biopharmaceutical company said semorinemab showed a statistically significant reduction in cognitive decline from baseline by 43.6% compared with placebo in the study. The study was being conducted by Roche Holding AG's Genentech unit, AC Immune's collaboration partner in Alzheimer's disease since 2006.

AC Immune said there was no effect on the other co-primary endpoint of reducing the rate of functional decline from baseline, adding that semorinemab was well tolerated in the study, with an acceptable safety profile and no unanticipated safety signals.

https://www.marketwatch.com/story/ac-immune-semorinemab-meets-co-primary-endpoint-in-alzheimer-s-disease-aciu-271630411441
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oldandintheway

08/31/21 11:08 AM

#328402 RE: Bourbon_on_my_cornflakes #328390

Normal reaction to a patent PR would be a 5% hit.
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RedShoulder

08/31/21 11:22 AM

#328405 RE: Bourbon_on_my_cornflakes #328390

Bourbon, ACIU news was company said semorinemab showed a statistically significant reduction in cognitive decline from baseline by 43.6% compared with placebo in the study.

Just slowed the decline, not improved.

That will be dead on arrival because they are so far behind as in years on the time line compared to our AD Ph-2b/3 in progress. A2-73 will be on the market with a strong SOC while they are still in trials.
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Bourbon_on_my_cornflakes

08/31/21 1:38 PM

#328432 RE: Bourbon_on_my_cornflakes #328390

Patent Update: SAVA +8%, ACIU +24%, AVXL +4%, ANVS +5%

ACIU news is what is moving the sector and AVXL today, not the patent.

Patent has ZERO IMPACT. No PR from Company showing on Yahoo Finance.

Heck we're NOW BEHIND discredited ANVS, which has nothing.


We're not taken seriously by market in alz race. Just for Rett and PDD.

Interim peek now!

WRONG: ACIU given appropriate after-lunch treatment by the market after that lukewarm bit of news.

Most alz stocks down from this mornings high by 50%, not just ACIU.

And ACIU are still up 24%

Expect AVXL to close over $20.00 per share TODAY and continue up TOMORROW!!!

Would be great but unlikely. Stick to forecasting GREAT NEWS and avoid easily verifiable numeric specificity.