Replies to post #397354 on NorthWest Biotherapeutics Inc (NWBO)

[X Master]

DCVax does not work on MRNA technology.

[hump4]

Simple answer is no.

[biosectinvestor]

It’a not mRNA technology. Not sure what you mea does it work “on” mRNA technology. It could be as good or better, it is another route to programming the immune system, it is not picking and choosing what targets but rather firing all of the targets, and not trying to discriminate and figure out if only a few will do the trick. Other vaccines have picked targets and the cancers evolved away, so they looked like they might work at first, but the cancer retired, just it with the targets of a selected antigen approach.

[biosectinvestor]

People are telling you no because the question doesn’t make sense and it is easier to say no than explain or figure it out with you.

DCVax itself is a cellular treatment. mRNA is a different technology. Both are new, both do similar things, but DCVax programs the master cell of the immune system with a whole target exposure, and mRNA takes bits of rna and gets cells to make those bits and then the body perceives the reprogrammed cells as “infected” and identifies the small bits of human chosen rna targets as a target. It is a cheap and easy way to execute a strategy that has been repeatedly previously tried, but has not worked well because tumors and cancers appear to adapt and evolve away from human designed vaccines that pick only very specific targets. DCVax identifies all the mutations in a given cell, not just the few targets chosen by a researcher.

Anyway people are telling you no, because your question is not really answerable.