Replies to post #386274 on NorthWest Biotherapeutics Inc (NWBO)

[jondoeuk]

You should listen again. Also, I'm pretty certain that Dr. Rosenberg (chief of surgery at the US NCI) is well aware of DCVax.

As for MRNA, a pilot trial was run, and from the paper: ''Neoantigens recognized by autologous TILs were identified by high-throughput immunologic screening using long peptides and tandem minigenes (TMGs) covering all mutated epitopes, as previously described (2, 11). In addition to the defined antigens, we also included any mutation in the TP53, KRAS, or PIK3CA driver genes and up to 15 in silico–predicted HLA-I potential neoantigens.'' https://www.jci.org/articles/view/134915