IMO the pill burden is overblown - I take dozens of pills/caps per day, V is a tiny fraction of them - my Dad, who has CVD, takes a bunch of stuff every day too. But you do point out the problem with this idea - you'd have to get docs to write scrips for the 500 mg dose and not 1 g - how do you make them do that when you are struggling to get them to prescribe V in the first place? You're essentially asking them to take an economic interest in AMRN.