The vast majority of short selling is by market-makers and the vast majority of those short transactions are matched with buy-to-close transactions within milliseconds.
Overnight shorting is only reported twice per month.
The best signal I am aware of for long-term shorting pressure on a stock is Interactive Brokers' Stock-Loan-Borrow (SLB) rate -- the interest rate they charge on borrowed shares. The SLB rates are at historic lows for AVXL, indicating there is no large-scale shorting, either individually or in the aggregate.
For a long time, I have alternated making my AVXL shares between available for lending and not available. When available, and there is demand, IB will lend out my shares, charge interest to the borrower, and pay me half the interest. I can see daily reports on how many of my shares they have lent. I have been leaving it as available ever since January as an extra way to monitor short demand. Since early February, almost none of my shares have been borrowed. The big shorts have apparently not recovered their capital or nerve from their meltdown caused by WallStreetBets.
News 
Market Data 
Discover 
AI
