PD, they don't lose the integrity of the trial even if they announce its topline results and give the data to FDA before publishing it. I don't know how they lose it unless there is a scientific misconduct. Otherwise, its integrity is determined when they designed the trial. In addition, FDA is more thorough than peer-review journals (eg, NEJM).
Anyway, whether they announce topline results or not, we need to wait the results until June or July.
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