The research was funded by the Wellcome Trust and the TRANSVAC2 project supported by the European Union’s Horizon 2020 Research and Innovation programme under grant agreement No 730964.
Trial shows York leishmaniasis vaccine safe and induces immune responses in patients
Naarden, The Netherlands and Munich, Germany – 20 April 2021 – Forbion, a leading European life sciences venture capital firm, today announces the final close of its Forbion Growth Opportunities Fund I (“Forbion Growth I") at the hard cap amount of EUR 360 million (USD 428 million). Forbion Growth I is focused on investing in late-stage European life sciences companies.
Pantheon, Eli Lilly and Company, Horizon Therapeutics plc (Nasdaq: HZNP), the Belgian Growth Fund
The lobbying disclosures show that Jeff Ricchetti lobbied the EOP for health-care giants GlaxoSmithKline, Horizon Therapeutics and Vaxart Inc.
Horizon Therapeutics paid Ricchetti $80,000 in the first quarter. He went on to lobby the EOP, Congress and the Department of Health and Human Services on their behalf, including on “issues related to drug pricing and Medicare and Medicaid reimbursement,” the quarterly document says.
A spokesman for Horizon declined to comment for this story.
“The urgent effort to develop a COVID-19 vaccine has focused on injectables and many policymakers don’t know that the Holy Grail is an oral tablet — an oral tablet is easier to distribute, administer, and is stable at room temperature, unlike injectables,” a company spokesman told CNBC. “It also overcomes needle-phobia that many Americans suffer from. We have asked Mr. Ricchetti to help us educate policy makers about the oral tablet option.”
- The company Vaxart (NASDAQ: VXRT) from San Francisco has been developing oral vaccinations against the diarrhea-causing norovirus and against the uterine cancer-causing papillomavirus for a long time.
Together with Janssen (subsidiary of Johnson & Johnson) she is developing an oral flu vaccination, which in a phase II study gave better results than an established injection vaccination - if confirmed by a phase III study, that would be an absolute sensation.
Vaxart's Covid vaccine gave good protection in animal studies, and a Phase I human trial produced cellular immunity and local Ig-A antibodies, but no IgG antibodies in serum, causing the share price to fall.
This seems unjustified because one in sixteen Covid healed people also has no serum antibodies , and because animal experiments have shown that cellular immunity protects against low levels of antibodies .
And if that vaccination prevented the virus from reaching the bloodstream, the lack of serum antibodies wouldn't be a disadvantage. Only clinical trials can clarify this.
Vaxart (VXRT) – Vaxart surged 18.6% in premarket trading after it reported positive results in a phase 1 trial of its oral Covid-19 vaccine. Vaxart said the vaccine could be just as effective as the injected vaccines developed by Pfizer and Moderna (MRNA).
They don't want to be a part of an equity stake w/ Big Pharma
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and Director of the Start-up and Spin-off Program from the Swiss Federal Institute of Technology in Lausanne (EPFL). During his tenure, more than 35 spin-offs were launched. In parallel, he served as expert for new ventures creation at the Swiss Federal Commission for Technology and Innovation (CTI) in Bern.