Support: 888-992-3836
Copyright © 2023 InvestorsHub Inc.
Replies to post #26 on MyMD Pharmaceuticals Inc (MYMD)
leifsmith
04/29/21 8:56 AM
#28 RE: SeanVan #26
Tumor Necrosis Factor (TNF) has a crucial role in inflammation, cell proliferation and cell death. Dysregulation of TNF receptor 1 (TNFR1)-induced Nuclear Factor-kappa B (NF-kB) signaling leads to chronic inflammation and is associated with several human inflammatory pathologies. Hence, TNF neutralization suppresses inflammation and attenuates inflammatory pathology. However, despite its beneficial effects, anti-TNF therapy suffers from efficacy issues and severe immune side effects. There is thus an urging [sic] need to identify novel targets for pharmaceutical intervention in the NF-kB signaling pathway.