As an analyst, this is what I would have imagined her saying. This is what throwing away the baby with bath water really means (although I would like to believe it’s more than just reference to single arm studies and she also has positive tld)
Fwiw I agree with the reasoning and not being a purist for sake of it. I can afford to be purist when I am ab testing idiots to get more likes or sell more toilet papers, not when it’s a matter of life and death.
Please pray she has good tld whatever your motivations maybe.
Thank you for that part on external control arms senti. The transcript is helpful and does provide some context for the slides.
Not surprising that she is a clinical trial purist, (just like ex :-) ) and was not initially fond of external control arms, but she lays out a pretty strong argument in support of them for GBM and other rare disease trials.