We can only keep guessing but these are not the kinds of changes a small science based company makes w/o good reason. Recent DOTs indicate both serious tech/medical news is near while AVXL gets ready lead/move on/direct others. These are not just more of the same news-moves.
These are the kinds of changes that people make when they are preparing to show/demo a new face while they link to new value added activities, like making stuff. IMO, they are reconfiguring to structure around what will be next.
IMO, the good news is, these are the kinds of actions a small company takes when the data-results warrant a build b/c the results are solid. AVXL would not do these things if results missed their targets.