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RedShoulder

03/18/21 9:59 AM

#303805 RE: Mikesc #303804

"Following a successful phase 2 trial, Cassava Sciences told investors the Food and Drug Administration (FDA) gave the green light for a pair of phase 3 trials slated to begin in the second half of the year. If simufilam succeeds at both, shares of this biotech could explode higher.

Unfortunately, Cassava Sciences has been developing simufilam for over a decade and it still doesn't have any evidence from a randomized controlled trial that simufilam works as intended.

The company included a placebo group in a small phase 2 study that read out last year, but simufilam failed to reduce signs of inflammation that show up in fluid that bathes the brain. Investigators also gave Alzheimer's disease patients cognitive tests to see if simufilam actually made a difference, but they couldn't measure an improvement."

Some WS analyst are indeed going to look like fools.

Many thanks Mike for the Fool's link:

https://www.fool.com/investing/2021/03/18/3-biotech-stocks-to-avoid-right-now/?fbclid=IwAR1zaX1223G_KZu1sTePWJ8axo6ZOel3jFVPAcnoYFDVu4_TTbnLCCTC7BU

nidan7500

03/18/21 10:14 AM

#303809 RE: Mikesc #303804

Mikesc; good catch
https://www.fool.com/investing/2021/03/18/3-biotech-stocks-to-avoid-right-now/?fbclid=IwAR1zaX1223G_KZu1sTePWJ8axo6ZOel3jFVPAcnoYFDVu4_TTbnLCCTC7BU


Following a successful phase 2 trial, Cassava Sciences told investors the Food and Drug Administration (FDA) gave the green light for a pair of phase 3 trials slated to begin in the second half of the year. If simufilam succeeds at both, shares of this biotech could explode higher.

Unfortunately, Cassava Sciences has been developing simufilam for over a decade and it still doesn't have any evidence from a randomized controlled trial that simufilam works as intended.

The company included a placebo group in a small phase 2 study that read out last year, but simufilam failed to reduce signs of inflammation that show up in fluid that bathes the brain. Investigators also gave Alzheimer's disease patients cognitive tests to see if simufilam actually made a difference, but they couldn't measure an improvement.

Tdeank1

03/18/21 10:19 AM

#303810 RE: Mikesc #303804

Too bad there isn't another bio with multiple controlled studies showing statistical significance, practical significance (effect sizes) and clinically meaningful outcomes...and with an ad study just about fully enrolled....now that would be a one in a billion stock to find...maybe one day

rayovacAAA

03/18/21 10:44 AM

#303816 RE: Mikesc #303804

THE AUTHOR OF THAT ARTICLE IS CORY RENAUER!!!!!!!



IS HE A RESPECTED ANALYST NOW AND NO LONGER A MEMBER OF THE CABAL TRYING TO KEEP A2-73 FROM THE SICK??????