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xodcode

02/25/21 2:52 PM

#300611 RE: TempePhil #300609

Also nice comment regarding Simar-1 gene variant and how results to date provide further evidence of the A2-73 MOA is via action on Sigmar-1.

Jonjones325

02/25/21 2:52 PM

#300612 RE: TempePhil #300609

I also liked his comment about the improvements seen in PDD.

Many PDD failures and in our trial people went in with a certain amount of dementia. Some cam out of the trial with less dementia!

Drop that mic!

RipperMagoo1

02/25/21 2:54 PM

#300614 RE: TempePhil #300609

Thanks Phil - the excitement makes sense of it being a pivotal study.

Perhaps then, the real sp catalyst then might actually be the result of the FDA meeting and confirmation of it being a pivotal study (several months later) rather than the top line results itself?