vg_future - By no means am I wishing for a return to single digits so that other posters here lose money. I want everyone to profit from AVXL - even Mike the Golfer! For me personally, to see a stock basically quadruple in a matter of just a few days on no news...you just gotta bank some profit. These types of "gifts" just don't come along every day. Many ways to play this game. Everyone should do what feels comfortable to them...plain and simple. Best of luck to you and everyone else here!