Replies to post #207 on Idenix Pharmaceuticals (IDIX)

[DewDiligence]

Here’s a thread on GI-5005 from
the BV board a few months ago:
#msg-14085633.

Regards, Dew

[rsox]

Hi, i recently posted that my mother was going to participate in the globeimmune study with the agent called (gi-5005). In going over some of the risks i come across a part that says the following,>>> After receiving the injection with the agent in the study, it is possible that your organism may produce antibodies against the yeast. the antibodies are molecules that the immune system produces to combat infections. These type of antibodies are observed in some patients with crohns disease. It has not been demonstrated the the antibodies cause crohns, but it has been detected in patients who have that disease.<<<

and a caution that any patient who suffers from intestinal inflamatory diseases or crohns or ulcerative colitis, can not participate in this study.

i am concerned that there had been an indication where this agent might cause chrons disease. Gi-5005 is modified through dna to produce a substance found in the hepatitis c virus.

do any of you medically educated folk on this board see anything that might cause some serious concern, or could you point me in any direction where i can further explore this?