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Dr Bala

12/19/20 9:05 AM

#340733 RE: tryn2 #340730

I don't think they will go through the trouble of a publication. Imo, it is all good news. The UCLA team already said in their conference this month, "There are many vaccines out there, Here at UCLA, we use the DC Vaccine." Even on their slides, they place the name of DCVax. Why keep on using it if it has no substantial benefit?
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exwannabe

12/19/20 9:50 AM

#340744 RE: tryn2 #340730

Question: do companies who complete failed trials go to the trouble of having the details of said trial PUBLISHED, when it is not required...??? I don't think so...(-:


You can think whatever you want, but they most certainly do publish failed trials.

A) It the ethical thing to do. Patients were put at risk, and the results (even for a failure) could help others avoid that.

B) For many trials it is a law.

C) "Publish or Perish" might be in academia, but plenty of overlap.


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biosectinvestor

12/19/20 10:07 AM

#340751 RE: tryn2 #340730

Usually yes, they do. But it’s not really just the company, it is the researchers. The other trials we have been discussing, that are being used fir historical comparison, some are in published research journals. I expect Dr. Liau and the entire group of doctors to publish DCVax no matter what.

I try not to find false reasons to presume success. I think the blinded data is adequate enough to fell fairly confident. But these other proxies, relying on laws that are not really what they are billed to be, or the assumption that a trial would not ever by published if it failed, are not useful measures for presuming “success”.

Also, I’ve learned over the years that superficially “obviously failed” trials are often not necessarily a complete failure and sometimes drugs eventually are approved out of that data.

People on bulletin boards and the markets operate in black and whites and shorts love to manipulate those feelings. Longs love to grasp at straws. What we have is extremely exciting blinded measures that clearly suggest that something dramatically good is happening with the patients in the trial. Once they release the data, we will have a fuller picture. Then there will be a publication.

A publication on a failed trial is just as important as one on a successful trial, especially a trial this data rich and important. So I’d presume it gets published no matter what.

I also think the company INTENDS to tell us the top line results as soon as they can, because they have said they will, repeatedly.