Interesting. Perhaps efficacy would shoot through the roof and would interrupt their timing? Exclusions later could mean a much larger population not admittable? Second guessing of course. Good point to be curious about.
I would think that vaccination would increase the number of CCR5 receptors making it more difficult for leronlimab to cover all receptors. In HIV the closer to 100% coverage the better the success rate. In cancer or other diseases involving cytokine blockade 100% is ideal but you'll see positive effects at lesser coverage.
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