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Re: Monroe1 post# 131753

Monday, 12/07/2020 1:52:38 PM

Monday, December 07, 2020 1:52:38 PM

Post# of 232975
I'm still baffled why some of the PRO140/Leronlimab clinical trials had exclusion criteria stating:

HIV-1

Any vaccination within 2 weeks prior to the first study dose



NASH

Administration of a live, attenuated vaccine within four weeks prior to start of PRO 140 treatment or anticipation that such a live attenuated vaccine will be required during the remainder of the study Note: Seasonal influenza vaccines for injection are generally inactivated flu vaccines and are allowed; however intranasal influenza vaccines (e.g., Flu-Mist®) are live attenuated vaccines, and are not allowed



The study posted earlier was a "theoretical" study from what I recall...or did they find something out as a result of clinical trials (tNBC or cancer basket) where it WASN'T an exclusion....

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