Replies to post #336226 on NorthWest Biotherapeutics Inc (NWBO)

[Doc logic]

exwannabe,

It took 5 years of waiting out the regulators mindset transitioning to make this change acceptable as applicable. The role of Dr Ashkan and Dr Linda Liau in all of this can not be overstated. Merck saw the writing on the wall, passed the ambassador Black screening test and is now positioned to make a major upgrade both short and long term to their business model. I believe that those with eyes to see can see this pretty clearly and are not selling their shares. Merck just sold their stake in Moderna which utilizes what many believe to be a competitive process to that of NWBO with mRNA. Now why would they do that unless something safer, just as or more effective and ready to hit the ground running with the right partner was being looked at? I don’t think they would. NWBO is soooo.. derisked that the kings of Wall Street are going to be made to look foolish by being so blind. As to playing games, that’s not me. I call it as I see it and the regulators have been changing their mindset as a new paradigm with immunotherapy has taken shape. Best wishes.

[marzan]

How did UK and Germany allow that change? Are they not regulators?? Did FDA not publish the guidance that allows such change? Like flipper says what do you know about LP et al about what they do or don't with the FDA that is already accessing the DcVaxL trial sata ever since they put the hold and lifted it and so forth so long that flipper is asking what is FDA going to look for consistent with the change or anything deviant from the change while they are already seeing the data. Just keep spinning as you like Ex, your time is up shortly, imo.

[sentiment_stocks]

The original endpoints are still part of the revised SAP, so we’ll still see how those turned out. But if the treatment arm in the L trial shows an average or a medium of, for example only, 25 to 27 months, and that 15 to 20% of the treatment arm lived well past historical averages for that same percentage, wouldn’t you want this treatment to be given regulatory approval? Let patients and their doctors then decide if they want to give DcVax a try.

I think most of us would agree that for the most part, Optune is a tremendous waste of money for a GBM sufferer. The price hardly seems worth the quality of life loss. Yet you do not fret and post 24/7 about that topic, and in fact, when you do discuss it here, you don’t seem to be at all bothered by it in the least.

So I really can’t comprehend what it is that you are so hung up about.