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XenaLives

11/29/20 12:41 PM

#285463 RE: Doc328 #285462

IMO the answer may be very simple - they do not want to report this data without being able to discuss it within the context of the actigraphy data and biomarkers.

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georgejjl

11/29/20 1:03 PM

#285467 RE: Doc328 #285462

Continuity of Attention (COA) Accuracy scores of the Choice Reaction Time and the Digit Vigilance tasks, minus the number of
false alarms



Broad and statistically significant improvements in CDR system Cognitive Domain of Attention assessed by Choice Reaction Time (p = 0.039) and Digital Vigilance (p = 0.008) and CDR system Episodic Memory (p = 0.047), representing complex cognitive tasks with impact on quality of life such as making a choice between similar objects and remembering daily personal experiences, which are mostly impaired in both PD and AD



Quality of Episodic Memory (QOEM) Accuracy scores of Word Recall, Word Recognition and Picture Recognition



See slide 4 at the following link:

https://www.anavex.com/wp-content/uploads/2020/11/CTAD-Anavex-PDD-001-Topline-data-Presentation-2020.pdf

GOD bless,

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rayovacAAA

11/29/20 2:30 PM

#285485 RE: Doc328 #285462

GREAT POST DOC328, WELL DONE!!!!
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Investor2014

11/30/20 5:11 AM

#285551 RE: Doc328 #285462

References to CDR are indeed very scarce. The inventor's website Wesnes Cognition is not secure and looks like a site from the 90'ties might look.

I did not find any studies, other than those designed to validate the Wesnes invention and the Anavex PDD trial, that had CDR-COA as an endpoint.