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dadbrotheroftwins

11/18/20 1:13 PM

#283945 RE: nidan7500 #283910

Well thought observation. Only problem is getting the product to the patients, and to do that you need approval, hence meeting endpoints. Changing a tire at 60mph, if you can find a method to do it would be great. Anavex has yet to start the car because they can't find the keys.
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Jonjones325

11/18/20 1:42 PM

#283950 RE: nidan7500 #283910

Agreed. I'm sure there are examples of drugs getting approved based on meeting partial endpoints.

We are so programed to focus on the pass/fail, black/white results, that we forget there is a wide spectrum in between.

Partial success is still success in light of these complicated diseases. It becomes a greater success when you can slap a SAFE label on it.

I believe the regulators are smarter than we think. They understand the detriment of staying in the pass/fail box.

Positive things are happening and have been happening. We will see them bear fruit shortly.
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vg_future

11/18/20 3:40 PM

#283958 RE: nidan7500 #283910

nidan7500, I would wait for the company to tell us if they missed end point...not some message board opinion. We have heard enough of this conjecture and endless repetition. It doesn't make it right...everyone is entitled to their own set of opinions, but not facts. Data presented at CTAD is AZ relevant....period....what is PDD related will be done later. Why the company chose to do that way, we can only opine. But, I would trust the company to take the best decision based on the data and strategic timing and moves.

-vg_future