Replies to post #278312 on Anavex Life Sciences Corp (AVXL)

[Jonjones325]

Good points. Although they are presenting PDD data, I believe they could present some supportive Alz data with it. After all it is an Alzheimer’s conference.

It would be great if they presented some OLE Alz data to show the consistent overlap in our hypothesis for CNS diseases.

Missling’s statement during the CC about proving our precision medicine approach on 3 different occasions would also be another good thing to highlight.

It’s an Alz conference so Missling must show relevance besides PDD being a form of dementia.

[boi568]

Anavex will be making an MOA demonstration at CTAD. There is no other way to look at this.

The interesting question, aside from the strength of the PDD data, is what data Missling will use from AD results.

[Investor2014]

From the LB25 programme slot.

- ANAVEX®2-73 (blarcamesine) Currently in Phase 2b/3 Early Alzheimer’s Disease (AD): Analysis of Cognitive Outcome
Measures Relevant in AD of Double-blind, Multicenter, Placebo-controlled Phase 2 Clinical Trial in 132 Patients with Parkinson’s
Disease Dementia

[XenaLives]

It just occurred to me that new diagnostic methods for Alzheimer's may also be announced at CTAD.

This would also be a plus for Anavex.

[tredenwater2]

Very good point Nidan. Who would know better than Dr Fadiran who is cranking out our paperwork for our trials and applications at an exceptional high rate based on what we currently see let alone whats happening behind the scenes. I rest easy knowing that Dr Missling has attracted some of the best Dr’s, in their prospective field, to help coordinate, calculate, and carry out the plan! If they go at Alzheimer’s proof of MOA through PDD than that would just be brilliant. I do recollect the comments made about many CNS symptoms being similiar across multiple diseases, why would the dementia aspect be any different than seizures, or sleep?

I again this morning was contemplating and marveling at the struggle and costs involved for a large pharma to come up with a drug, for sometimes treating only 1 of many symptoms of a disease and its like they hit a home run. Then, after they get the 3 billion bump in MC the consumer gets the laundry list of side effects. If we continue on our path of symptomatic relief, with little to no side effects, this will be equivalent to hitting a grand slam.....for each disease! It would be like one of those 21-0 baseball games. The problem we face is that we are currently coming up to the plate in triple aaa, will the big boys allow us to play in their big stadium or are they going to buyout out our “farm” and close us down?

Imo again, Dr M is brilliant in how he haslined up the trials to coincide with each other!

Cheers