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Rockleo

10/22/20 5:12 AM

#125465 RE: ohm20 #125461

ohm20... WOW.. Wasn’t aware of this 2nd mechanism of action attributed to Leronlimab..!!! So Leronlimab already has..What these scientists are intending to develop..!!!

Thank you..!!!

daemon57

10/22/20 5:50 AM

#125466 RE: ohm20 #125461

ohm20 - thanks for constantly contributing this type of great information. I really do appreciate it.

BTW - your list of treatments LL can potentially account for is dizzying!

GLTU/A.

misiu143

10/22/20 5:50 AM

#125467 RE: ohm20 #125461

Ohm , great information ,
What else we will discover with this virus and our Leronlimab ..

So this is at lest one of the reason why even early in the infection Leronlimab is working.

Until now I mostly though of indirect antiviral effect , by repairing in more severe patients damage immune system .

Very interesting , thank you .

Amatuer17

10/22/20 6:54 AM

#125468 RE: ohm20 #125461

Good find but how it is connected directly to Lero? Where you got the information that Lero blocks neutrophils?


“If you think of ACE2 as a door lock to enter the cell, then neuropilin-1 could be a factor that directs the virus to the door. ACE2 is expressed at very low levels in most cells. Thus, it is not easy for the virus to find doors to enter. Other factors such as neuropilin-1 might help the virus finding its door,” said Balistreri.”

ombowstring

10/22/20 7:49 AM

#125469 RE: ohm20 #125461

I don't understand this. I thought leronlimab's MOA against COVID was occupying the CCR5 receptor, but

"It has been shown previously that SARS-CoV-2 uses the ACE2 receptor to infect human cells."

Rock, misiu, can you clarify this for me? How does leronlimab work, how does it calm the cytokine storm?

SmileyRiley_595

10/22/20 8:15 AM

#125473 RE: ohm20 #125461

That’s the good stuff Ohm!!! Good to have people like you sharing this type of knowledge!!!

lostmyballs

10/22/20 8:41 AM

#125477 RE: ohm20 #125461

You outlined it after reading what info ?? Link please