Replies to post #324189 on Innovation Pharmaceuticals Inc (IPIX)

[wsbc]

Heh, no worries. I just wanted to clarify. ;)

Non-peptidic structure also helps with simplification for manufacturing.
Hoping post-positive P2 results for SARS CoV-2 (if we get there) this will pay dividends with respect to manufacturing speed on the back-end. If there's a vertically-integrated partner involved, manufacturing domestically in-house should be a reality.

I just realized I didn’t answer the question. For a simplified answer for what the molecule is that mimics a defensin peptide I went to Wiki: “... is an arylamide foldamer designed to replicate the amphiphilic properties of antimicrobial peptides while solving the problems encountered by peptide-based antimicrobials.”

Defensin peptide mimitics are artificial molecules that mimic the ability of proteins, nucleic acids, and polysaccharides to fold into well-defined conformations, such as helices and ß-sheets.

Arylamide foldamer: an aromatic ring molecule containing peptide bonds that folds on itself. “ They are artificial molecules that mimic the ability of proteins, nucleic acids, and polysaccharides to fold into well-defined conformations, such as helices and ß-sheets.”

Yes, Brilacidin is a non-peptide mimetic.