I think we have about a 60% chance of approval. It's been creeping up over the years. I think in 2017 I had this pegged at around a 30% chance but the data we've seen has been positive since then. It's still a big risk, the share price would be a lot more than $4.35 if it were a sure thing, but I think the precision medicine targeting bumps the odds up slightly compared to if AVXL were just testing random people without using biomarkers.