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schaef

07/21/20 1:43 PM

#96677 RE: schaef #96671

Actually I misread your comment "p = .06" as "p = .6" -- I forget how the statistical significance was measured, maybe you can refresh what that means.

The updated post says they were pleased that the results were "clinically meaningful", which doesn't sound like a hard scientific term.

bobshmob

07/21/20 1:49 PM

#96685 RE: schaef #96671

maybe...I did two tests (one-sided): a Mantel-Haenszel test on the odds ratio (p = 0.06) and a two-sample binomial test on the difference in proportions (p = 0.07). I presume they are using Mantel-Haenszel (or, equivalently, logistic regression), but what did you use to get p < 0.05?

[NOTE: One-sided tests on the efficacy side, but they might instead be doing two-sided tests on the safety data, in which the p-values would double.]