"clinically meaningful" for the particular patients in the trial.
"Statistically significant" would mean that the results are clear enough to extrapolate to patients in general because they cannot be reasonably explained by random chance.
Example...suppose one patient was given a placebo and ended up on a ventilator, while another got the treatment drug and went home the next day. That's clinically meaningful for those two patients but the sample size is too small to say anything about whether the same kinds of results could be expected for patients in general.
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