Replies to post #303821 on Innovation Pharmaceuticals Inc (IPIX)

[LIVED]

I would also add. The bar is set so ridiculously low, that if we show any benefit above remdesivir, we take over top spot.

[PlentyParanoid]

Stating things a bit differently: Why those old ABSSSI trials now have new importance, besides safety information?

One of the reasons why promising cell line results often fail to show up in tests with real life subjects (in vivo) is the fact that cell line is not representative of full human biology - not all human biological processes are present. This difference may result in a compound that was stable in vitro being metabolized to ineffectual form in vivo - a failure.

However, thanks to ABSSSI trials, we DO know that this is unlikely to be the case with Brilacidin.

[To infinity and beyond!]

Even when I believed strongly that RBL lung cell data failed I still had doubts. And yet you have none? Really? You may turn out to be right and maybe in 2-3 months we will know a lot more, or will it take 4-6, hard to say. One suspects they will push it quickly if the RBL papers are that good.

What happened to B OM? Same drug. Same great preclinical data. Sonis model predicted success and had done well before with other drugs. Interim data sensational. Final data not ready for prime time and no deal.

We may be right back at B OM outcome with B for c.

But maybe we will be stopping off the transport ship onto the (no longer Lonely) planet where B has trounced c and we can greet you in that singular space.

I hope that you are right and that human trials are successful

[KMBJN]

Why are you speaking in riddles? What semantics am I playing with and what am I subtly tiptoeing and acting about, in your opinion?

Just because I disagree with your wild 100% certainty that brilacidin will be a cure for Covid-19, acute kidney injury, and can treat "all flu pandemics" and "head and neck cancer," doesn't mean that I am short ("I'd go bullish if you haven't already!"). I have stated many times that I own shares, am optimistic (or else why would I own shares?), and have added more on the way down.

"100% probability of success like what I'd think it will do"

and

"I sense a $600+ mil valuation backed up with at least one phase II in moderate CV19 trial patients plus a small grant funding is very attainable."

You thus state you are 100% certain that this stock will go to $2, a >4x return from here. You must have all your net worth invested in this stock, right, since you are 100% certain? In fact you should be borrowing money to invest here, right?

If so, IMO, that is sheer lunacy. Nothing is 100% certain. "What you believe or how to wish to profit on that information is up to you."

"The results in two human epithelial cells were simply astonishing, I must say. Did you see it coming?"

After reading and commenting about brilacidin's potential antiviral properties, I was optimistic, yes, and thought it was a good possibility.

See my comments in previous posts (here are a few from March and April discussing the science):

https://investorshub.advfn.com/boards/read_msg.aspx?message_id=155141900

https://investorshub.advfn.com/boards/read_msg.aspx?message_id=154731403

https://investorshub.advfn.com/boards/read_msg.aspx?message_id=154253881

and on and on ...


I'm guessing you are claiming that you saw it coming. When did you first know that brilacidin would be successful against coronavirus and decide to invest? Looks like your first post here on ihub was May 4th.



Regarding "There's no doubt in my mind that Bril will succeed with endpoints set so low. What you believe or how to wish to profit on that information is up to you." How can anyone profit on the information about your convictions?