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Whalatane

06/15/20 5:40 PM

#233084 RE: dewophile #233080

dewophile No by all means please "butt in " ...thats why I read this board ...for informed views.
What I read was

Results: Twelve patients were treated with lenzilumab. Clinical improvement was observed in 11 out of 12 (92%), with a median time to discharge of 5 days. There was a significant improvement in oxygenation: The proportion of patients with SpO2/FiO2 < 315 at the end of observation was 8% vs. compared to 67% at baseline (p=0.00015). A significant improvement in mean CRP and IL-6 values on day 3 following lenzilumab administration was also observed (137.3 mg/L vs 51.2 mg/L, p = 0.040; 26.8 pg/mL vs 16.1 pg/mL, p = 0.035; respectively



Can you link me to what you were reading .
thx
Are you saying that because there was no placebo arm there's no way to know if these results are better than placebo ...unpowered study etc .

I agree ..a lot of limitations re the study
Kiwi

PS. Their P 3 double blinded placebo controlled trial is underway ...with an interim analysis ...so we should have some conclusive data fairly soon ...before yr end