Replies to post #286407 on NorthWest Biotherapeutics Inc (NWBO)

[jammyjames]

So she's saying the trial very likely formally failed for OS but doesn't even seem to realize it

[jammyjames]

Also she clearly doesn't know her own data very well. She gave a very misleading description of the results. Basically she should have stated exactly what was stated in the paper:

"With immune-based therapies, a key focus is on the tail of the survival curve [26]. Among the ITT patients with a surgery date?≥?30 months prior to the data collection (n = 223), 30% (n = 67) have lived?≥?30 months, and their KM-derived mOS estimate is 46.5 months. Among the ITT patients with a surgery date ≥ 36 months prior to the data collection (n = 182), 24.2% (n = 44) have lived ≥ 36 months and their KM-derived mOS estimate is 88.2 months."

[scotty3371]

Watched video, she has it all wrong. 22:11 mark numbers are incorrect.

[antihama]

I know posters who have # crunched the data for PFS feel it might be SS but after hearing her response to the last Q and stating (paraphrasing) 'whether DCVax was given early or late, they are all living longer' do they dare keep PFS as a co-primary endpoint and splitting the alpha in doing so or do they give all the alpha to OS as the single primary endpoint. I'd be so surprised if PFS is still a primary endpoint.