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Irishmick8299

05/22/20 7:51 PM

#252144 RE: Jonjones325 #252141

Nice post, hope we get a big chunk of that iceberg!
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nidan7500

05/22/20 8:12 PM

#252146 RE: Jonjones325 #252141

jonjones

The homeostasis thesis and the precision medicine thesis must stay intact. That is who we branded ourselves to be.

If the OLE data puts us in a better light, it should be shown.

Let’s hope there’s no need for spin and let’s hope we get the answer to the nagging low dose question. I don’t believe Missling would have chosen that dose when the data showed something else to be better. If he did it because he was scared of possible adverse effects. That’s bull.

He has been fearless all this time and when it’s showtime you chicken out. Don’t think so. You follow the data. That’s what he has always done and I believe that’s what he did.

When you see what we did and why, you will understand. Oh man. I hope so.



I agree w/your assessment of Dr. M.' style and cultural integrity. He is also not the kind of guy to risk a big failure due to lack of data and preparation. We do not know how much or what kind of data he does have but OLE data must be at least a piece by reason. Another factor we need to keep in mind is that no one has ever had any real CNS treatment success before now. (it's a 1 or a 0) He has data, he is in the left seat (PIC), he knows exactly where to land. Although there is still some science to get through one good thing about science is, it is what it is. Golden, IMO. As we say in the NAVY.."CALL the BALL"...Roger ball.