Replies to post #275280 on Amarin Corp Plc (AMRN)

[KevGee59]

JL has always said that he gave it to patients 1 to 2 weeks prior to surgery. And it had great healing effects.

Would love to see him give his opinion on this little pilot study.

KG ;)

[bfost]

Not sure what the big deal is here on the pro or con side

This is a put your toe in the water small study to see if V has an effect on inflammatory and thrombotic markers in COVID. If it's positive then they will likely do a small study to see if it has any clinical utility with a placebo control. If that is positive they will do a larger study.

I view this as a very small and initial positive with some future potential.

We know long term use of V is great but we don't know much about it's use for an acute treatment of an illness.

If it turns out it has acute benefits it would be HUGE! Do you know how relatively common ARDS and severe sepsis is (non covid)?

I'd personally be surprised if it has a significant clinical outcome benefits acutely but I'd love to be proven wrong.

[jessellivermore]

TTE...

Quote..Where is inflammation expert JL when we need him?...

Recovering from vascular surgery...

Cytokine storm occurs when things are wildly out of control..Classicaly occurring in systemic infections..Toxins are frequently involved more likely in conditions like gram negative septicemia...
I would comment more.. but the problem is much different than EPA/AA imbalances which lead to slow moldering chronic increased SI..Its like trying to compare a summer heatwave to a forest fire..

I have refrained from commenting on using Vascepa in treating COVID-19 cases because anything I say would just be speculation..It is possible it might help in COVID pneumonias...At present I am more interested in the up coming Appeal.

":>) JL