Replies to post #250062 on Anavex Life Sciences Corp (AVXL)

[TWilson07]

When crafted correctly, any statement can come off as factual. Honestly, it’s quite the art. In reality though, I will wait for my information to come from the individuals that work for the company and actually know what is transpiring.

[Steady_T]

The data from the P1 and P2a trials shows that to be the case.

[F1ash]

“Dizziness was the most common adverse event (20 incidents in 15 patients), followed by headache (16 in 10 patients). Most (94%) occurred in the first week of treatment. All were mild or moderate. Headache and dizziness are considered signs that patients are approaching their maximum tolerated dose, Dr. Missling said.

The company’s task now is to find a standard minimum dose that is strong enough to get patients to at least 4 ng/mL plasma level, without inducing these side effects.


https://www.mdedge.com/neurology/article/152595/alzheimers-cognition/development-sigma-1-receptor-agonist-alzheimers

[frrol]

I read the results on tolerability. Isn't that strange? ;-)