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My5cents

05/09/20 1:12 PM

#34724 RE: caltrials #34723

Plenty of people here can respond to this from the perspective of a shareholder interested in financial returns.

Even if I never get a single dollar back (though I expect to), I will be thrilled to think that my financial backing of this company helped save so many lives. I also think it will save many more than 75,000, from more things than "just" Covid-19.
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xov

05/09/20 1:48 PM

#34725 RE: caltrials #34723

If PLX is effective and becomes the standard of care for serious cases, then it could be used globally. If it’s perceived to be effective not just for COVID-19 but also for other viruses that cause pneumonia and ARDS, then its use expands even further. It could even potentially be stockpiled in anticipation of future pandemics. I realize those are big IFs, but the potential is there.
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zzaatt

05/09/20 2:14 PM

#34728 RE: caltrials #34723

why everyone is so excited about PLX cells and covid? It's not like there will be massive dosing.

Because it will move a small, relatively unknown Israeli company into the position of being the premier stem cell company, and because it will be the first time that stem cells will have been proven as a valid new therapeutic tool. You can only guess the effect that will have on the valuation, irrespective of how many doses are be sold.


Calculating the number of patients at this point is rather futile. Too many unknown variables such as:

1. Do you give the cells to patients only in extreme condition, or early on to prevent serious damage. If the latter, you increase the number of patients by an order of magnitude.

2. For all the flattening of the curve, we don't really know how many patients will need the cells, will there be a recurrence of very high infection rates in the fall, in the spring?

3. As far as number of patients, will you add the needs of China, India, Russia, the whole of the Eu.

4. Will the cells be used as a general pneumonia drug?

As I said before, there's not going to be a shortage of patients.

If Pluristem moves the still shadowy medicine of stem cells into big time, the reward will be very impressive. We still need to move out of the realm of copper bracelets for cancer, to real SOC medicine in ANY indication, with pneumonia as a pretty good start.