I have never seen an indication written on a prescription. When the pharmacist sees the script he has no idea what the doc is writing it for. So if there is no "no generic substitution" written on the script he will sub if there is a generic available.
I am with pharmadude and Cardiologymd on this one. The difference now is that EPA (thanks to Amarin) has demonstrated benefit in cardiovascular disease. So regardless of the label, pharmacists could as far as I understand substitute for the generic regardless of the official label.
Look they are still substituting Vascepa for omega-3 which is even a more puzzling situation even today.
JL: Could you see a Cardiologist actually prescribing an unapproved Generic for a Heart Condition? I would think they would want to stay so far away from something like that...