Replies to post #262412 on Amarin Corp Plc (AMRN)

[Meowza]

Nice!

Also, i'm mad!

[Laurent Maldague]

yeah, seems like clear factual error

There's no equivocating around it this time.

"statistically-significant differential effects reported between the EPA and control groups"

Apo-B unexpected result restored would be hugely favorable

[IgnoranceIsBliss]

Oh my God mc1988 you are absolutely right. There is no significant difference between EPA and control at any point in time.

This is just like Mori — there is a significant difference for EPA between time 0 and 48 weeks, but that’s it.

This is an enormously important distinction— another sloppy non-POSA-like misinterpretation of the data!

This is something I would share with AMRN management!!!

[IgnoranceIsBliss]

That statement from Du is literally patently factually erroneous! The table in the paper flatly contradicts that statement!!!

[amarininvestor]

Excellent. I think that means she understand the right way of interpreting the experiment

[circuitcity]

Really brilliant!!

[MNBioMike]

Wowza. I'm sure Covey/Kennedy are all over this, but it should definitely be passed along to Amarin ASAP.

[circuitcity]

Just trying to be precise, and maybe devil advocate here:

Quote:
—

In light of the statistically-significant differential effects reported between the EPA and control groups, a POSA would have attributed the reduction in Apo B to EPA. (Id. at 737:24-738:8.)
—

The first half is wrong as you put it, but the 2nd half, after the space I put in, is subjective.

[Freifaller]

Hello,

I´m neither a pharma guy, nor a statistican and so I don´t get it. What is exactly wrong with this?

With the sentence:

In light of the statistically-significant differential effects reported between the EPA and control groups

...do you mean, that she can´t compare the EPA Group to Control Group?

So...
EPA was over time statistically significant
Control Group was not statistically significant over time.

She states the statistical-significance between both Groups and this is wrong? If so, why is this wrong? Is this not statistically significant because the difference is too less….I mean, if you compare both Groups...???

[rmitra]

Sorry reponding to wrong post

[dukesking]

I haven’t seen where anybody sent this to IR so I did. I mentioned that many of the posters on Ihub feel this may be very important and relative information for the Amarin team. FYI

[concapk]

Please send this to Elisabeth (IR ) at AMARIN.... she will forward accordingly..