Replies to post #272905 on NorthWest Biotherapeutics Inc (NWBO)

[manibiotech]

On the same token I haven’t heard praising how NWBO trial was designed either .

[CaptainObvious]

Appears??? She out and out said it.

[exwannabe]

I think it is interesting that she asserts there was no true placebo arm.

I assume that she is talking about the percent of patient who elected to use Optune off label after being assigned to placebo. Well, that is not a design issue. a patient can always elect to break protocol for an alternative treatment if the want. That is really a basic right. And Optune was already on the market so any patient was free to use it.

So not a design issue at all, just a fact of life that always makes it harder to show OS in front line when the drug is already approved.

Now, if she is talking about the confounding effect, yes it happens. Optune showed P < .05 despite it.

Maybe we will know DCvax-L results by next ASCO (which I expect in 2021).

[Lykiri]

ATLnsider,

Thank you for posting this:https://billmalloy.info/qa-with-linda-liau/

March 23

Bill Malloy
@bmalloyIII

My very personal interview with Linda Liau at #UCLA who saved my #wife's life in our battle with #cancer and #glioblastoma

Q&A with Linda Liau | Bill Malloy
Dr. Linda Liau is widely recognized as one of the world’s most forward-thinking brain surgeons.
https://billmalloy.info/qa-with-linda-liau/

My very personal interview with Linda Liau at #UCLA who saved my #wife's life in our battle with #cancer and #glioblastoma
@sloan_kettering @UCLA @theNCI @parkerici @StanfordMed @cityofhope @briansin @JoeBiden https://t.co/8VOIz9gGdz

— Bill Malloy (@bmalloyIII) March 23, 2020

About Bill Malloy: https://billmalloy.info/bill-malloy-financier-and-technologist/

Sway Ventures video:

This Sway Minds Technology Summit 2019 Healthcare Panel explores the $9B question, is the cost of drug development killing us? Can digital health save us?

Linda M. Liau, MD, PhD, MBA Neurosurgeon and Professor of Neurosurgery at the David Geffen School of Medicine at UCLA
Samuel R. Browd, MD, PhD Professor of Neurological Surgery
John Norris, JD, MBA Former Principal Deputy Commissioner (COO) at the FDA
Daniel Haders II, PhD Operating Partner at Sway Ventures

moderated by Bill Malloy Founding General Partner at Sway Ventures