It wasn't easy to hang in there for 33 years. I bought and sold a few times but believed in the science and the public need as one of my best friends died a horrible death with H&N Ca in his mid 50's. I also knew that the average time for a new drug to reach the market is 10-12 years from discovery to FDA approval and sale. Clinical trials 6-7 years and average cost 2-3 BILLION. That is why I have a low tolerance for those complaining about a young drug like AVXL not being on the market today.