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GD

10/31/19 3:55 PM

#16494 RE: Biobonic #16493

I think I wrote my opinions here on many posts, it just
makes scientific sense Thermodox is working to kill the
distant small HCC tumors RFA can not do, if we believe
Thermodox work, then OPTIMA should repeat the subgroup
results, since HR is almost constant after enough events
and KM curve separation, first look HR is the final HR
which should be 0.65 or less, that is the reason I place
a high chance of stop for efficacy.