Celsion Corporation (CLSN)

[Biobonic]

True that on DD

Tell, why do you believe that efficacy is a possibility? And what is the percent chance of that?

? Are there enough enrollees with enough time in the trial to make a solid measurement and see a differentiation between the two groups?

This is what I have so far: Dug thru a few annual reports.

The first trial did not meet the primary endpoints.

In follow up some things came to light:

Perhaps the Thermodox was not heated to the correct temp.

Perhaps the dwell time of the Thermodox in the tumor was insufficient.

The overall survival (years past the end of the trial) of the Thermodox treated group is very impressive.

So Celsion basically restructured the trial with the findings from the first trial.