Replies to post #248552 on NorthWest Biotherapeutics Inc (NWBO)

[longfellow95]

The P value is for the entire OS (or PFS) data. It is not for the median/landmark/HR/restricted mean datapoint. If median. mean, 36 month and H/R OS are all presented, there is one P value for all.

I disagree.

[jammyjames]

" Yes, the relative risk reduction is H/R in another flavor. "

this is my whole point. Maybe i was a bit sloppy with my wording using Hazard ratio and relative risk reduction as if they were the same thing. The point is that you don't need to do any cox regression or have any sort of implied model to measure a relative risk reduction. That single number relative risk reduction in combination with the log rank stat p-value should constitute the top-line (again possibly with some adjustment for cross-over). Now Bog off!;-p