Replies to post #215329 on Anavex Life Sciences Corp (AVXL)

[polarbear77]

Very interesting and important (for Anavex) publication released yesterday 10/18/19. Thank you georgegii.

“Metabolic Mitochondria Dysfunction May Be Primary Cause of Alzheimer’s
A team of researchers led by Yale-NUS College says it has found evidence that metabolic dysfunction is a primary cause of Alzheimer’s disease.”
https://www.genengnews.com/news/metabolic-mitochondria-dysfunction-may-be-primary-cause-of-alzheimers/


And just 5 days ago Alzheimer’s News Today has this to say about our compound:

“Anavex 2-73 is a small molecule that activates the sigma-1 receptor, which is known to modulate cellular processes relevant to neurodegeneration. Specifically, Anavex 2-73 is thought to help restore cellular balance by targeting protein misfolding (when proteins fail to fold correctly, into a normal configuration, they do not work as intended), oxidative stress (which damages cells due oxygen molecules with free radicals, or unpaired electrons), mitochondrial dysfunction, inflammation, and cellular stress.”

https://alzheimersnewstoday.com/anavex-2-73/

The picture is coming more and more into focus. At least for those willing to think clearly.

[Bourbon_on_my_cornflakes]

Metabolic and mitochondrial dysfunctions should be viewed as fundamental features of aging in general and that age-dependent diseases, including Alzheimer’s, should, therefore, be viewed as manifestations of aging.

Hence, it may be easier to prevent or treat age-dependent diseases by targeting the mechanisms of aging rather than treating individual diseases after symptoms occur.

In our regard, might Anavex 2-73 yield youth-preserving, anti-aging outcomes? Given it’s various mechanisms of action related to the preservation and restoration of general cellular homeostasis (proper control and operation of biochemical cascades and pathways; facilitated function of organelles, etc.) Anavex 2-73 might, to a degree, be the elixir Ponce de León was searching for.

Sounds right up 273's alley. A compound that restored cellular homeostasis would fit the bill as an anti-aging tonic.