Pricing is deceptive and often wrong in my experience.
The fact that all of the scientists and management are spending incredible resources on 4 SAP's says that they sincerely believe otherwise. So it's not just the math and science revealed in the unblinded journal article and presentations, and patient testimonials, it is the behavior of management. Duffy would not have come over, and he has substantial experience with trials, from his resume, if he thought this trial had failed.
There is a loud and very emphatic small choir who say otherwise, but they've been flatly and badly wrong a number of times now.