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JWC3

09/30/19 3:53 PM

#212272 RE: DoubleJ23 #212270

Dr Missling CEO of Anavex is only producing positive results.

POSITIVE RESULTS 100%.
NEGATIVE RESULTS 0%.


Nothing negative has been constructively produced that counters the use of Anavex 2-73 as a medicine that produces disease modifying benefits in Alzheimer’s , Parkinson’s Dimentia, or Rett Syndrome Diseases.

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Investor2014

09/30/19 3:53 PM

#212273 RE: DoubleJ23 #212270

The missing piece of information is what dose and dosing scheme and/or other factors are required to achieve a >= 4ng/nL A2-73 blood concentration.

We know that the first 4 weeks of the original 12 week Rett study design is for Dose Titration. We don't how many patients reach >= 4ng/nL A2-73 blood concentration or if it is still considered important.