At least one absolute super responder, Subject 107001 ABSOLUTELY AMAZING
Despite the small sample size, Preliminary data demonstrates Encouraging Safety and Efficacy Signal on both Caregiver & Clinician-based measures of Severity • Correlations with Key Biomarker related to disease Pathogenesis • High Level of Significance: Magnitude of change (Cohen’s d: RSBQ Total 1.47; Cohen’s d: Glutamate 1.11, Large-Very Large Effect Sizes), Short duration of treatment, Older age of participants, and Clinical significance (RSBQ-CGI-I correlations) • Anavex Rett Syndrome Program consisting of 3 clinical RTT studies including pediatric ongoing (U.S. RTT, AVATAR and EXCELLENCE)
At least one absolute super responder, Subject 107001 ABSOLUTELY AMAZING