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abeta

09/13/19 1:42 AM

#244039 RE: Umibe5690 #244037

You kinda said .....

M+ == pro-neural
M- == mesenchymal(MES), classical and neural.
M+ is not as aggressive as M-

If the abstract cited is accurate, this bodes extremely well for DC VAX as it appears to be very efficacious
for M+(pro-neural and 40% of trial ITT and 45% of overall categorised group--N=293) and a significant
percentage of M- due to MES. This would cover at least 50% of all ndGBM!

I was kinda gonna shoot back that this -- very efficacious
for M+(pro-neural and 40% of trial ITT -- can't be right as the % too high ......

So I set out to get the graphs to prove it ......

Then bumped into this 2019 ditty .....

https://www.ncbi.nlm.nih.gov/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Click%20on%20image%20to%20zoom&p=PMC3&id=6520485_41598_2019_43173_Fig2_HTML.jpg


https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520485/

I was wrong - again -

anyway

Idunno

09/13/19 3:48 AM

#244044 RE: Umibe5690 #244037

Umibe, good to see you’re interest in NWBO is strong as ever! Never waned, I guess....at least regarding their science. It’s just “the management” of that science (with their “secret sauce”!), I guess, that you’ve had issues with. Well, hopefully, with your new found admiration of the “Duffy hire”, (apparently you see his value!), you’re feeling better about management. Umibe, more importantly, (well, to you, none of my business, really, so forgive me), how’s the tea business? Sounds beautiful, your location there in Japan. So much beauty in the world! Best.