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georgejjl

09/13/19 12:05 AM

#209464 RE: falconer66a #209463

Before, during and after listening to Dr. Missling's recent presentation look at the PowerPoint below especially slides 11, 12 and 13

https://www.anavex.com/wp-content/uploads/2019/03/Anavex-Presentation-March-2019-1.pdf

Dr. Missling’s presentation.

https://www.anavex.com/wp-content/uploads/2019/09/Janney-Audio-Presentation-Sept-2019.mp3

Good luck and GOD bless,

plexrec

09/13/19 1:01 AM

#209468 RE: falconer66a #209463

falconer-"“activities of daily living almost not declining."very very nice---I must conclude--"we've got this" !!!!!!

Steady_T

09/13/19 1:20 AM

#209470 RE: falconer66a #209463

Falconer66a If you listen closely Missling is still using the concentration as the metric for the various results.

At the beginning of the presentation he uses dose and then says dose is correlated with concentration and people with higher concentration did better. Later in the presentation he mostly uses concentration as the measure for correlating with results.

If you weren't paying very close attention, you wouldn't pick up on that.

I did like that he discussed the new AD trial as having a number of different biomarkers being measured in the trial. I think these are new biomarkers in AD trials.

I think they are looking for biomarkers that demonstrate improvement as a result of taking 2-73.

nidan7500

09/13/19 8:55 AM

#209487 RE: falconer66a #209463

falconer66a

At three years (148 seeks), “activities of daily living almost not declining....” The plot line is almost flat. Cognition, too, continues during the period without notable decline.



Nice. I am also thinking they (Australia) may be using some kind of ERP device (portable-non intrusive) wireless monitoring of patients to get hard data-direct measurements of audio/light/smell/other.

plexrec

09/14/19 1:37 AM

#209640 RE: falconer66a #209463

falconer--" Anavex 2-73, at the right dosage, essentially stops the progression of mental decline caused by Alzheimer’s disease"--powerful words indeed---The Aussie Medical Ethics Committee surely is aware of these findings---what is holding up their conditional approval for 2-73 ??? With so many people who could benefit !!!!Anyway to contact them and give them a suggestion ???? I may have to investigate !!