Participants will be asked to complete a baseline visit, with yearly follow-up visits for up to five years. During a visit, participants will be asked to: Give a small blood sample Give a small urine sample Complete a 45-minute survey about their marijuana, alcohol, and drug use, sexual activity, pain levels, and mood Complete approximately 2 hours of thinking and memory tasks on paper and on an iPad The study would like to ask the participants to analyze the marijuana product that they consume using the MyDx device. This will be done by allowing participants to take the device home with a study phone that has the app on it to do a one-time test of their marijuana product.